Title : Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines.

Pub. Date : 2007 Mar

PMID : 17273769






2 Functional Relationships(s)
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1 Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines. Fenretinide TNF superfamily member 10 Homo sapiens
2 These results indicate that fenretinide-induced apoptosis is sensitized by TRAIL. Fenretinide TNF superfamily member 10 Homo sapiens