Title : Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS.

Pub. Date : 2007 May

PMID : 17272831






1 Functional Relationships(s)
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Protein Name
Organism
1 Mevalonic acid, the product of HMG-CoA reductase, was converted to mevalonolactone (MVL) in an incubation mixture, extracted by a salting-out procedure, derivatized into the mevalonyl-(2-pyrrolidin-1-yl-ethyl)-amide, and then purified using a disposable silica cartridge. mevalonolactone 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens