Pub. Date : 1992 Jan
PMID : 1727055
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NaB also induces TGF-beta mRNA in the maturing suprabasal compartment, suggesting that TGF-beta may play a role in NaB-initiated NHEK differentiation. | nab | transforming growth factor beta 1 | Homo sapiens |
| 2 | NaB also induces TGF-beta mRNA in the maturing suprabasal compartment, suggesting that TGF-beta may play a role in NaB-initiated NHEK differentiation. | nab | transforming growth factor beta 1 | Homo sapiens |
| 3 | NaB also induces TGF-beta mRNA in the maturing suprabasal compartment, suggesting that TGF-beta may play a role in NaB-initiated NHEK differentiation. | nab | transforming growth factor beta 1 | Homo sapiens |
| 4 | TGF-beta 1 was quite effective in inducing significant levels of CE expression when used simultaneously with suboptimal concentrations of NaB. | nab | transforming growth factor beta 1 | Homo sapiens |
| 5 | The cooperative action of suboptimal NaB and TGF-beta 1 generated numbers of CEs which, in fact, exceeded the incidence of mature CEs formed in response to optimal levels of NaB alone. | nab | transforming growth factor beta 1 | Homo sapiens |
| 6 | Neutralizing antibodies to TGF-beta, moreover, effectively reduced the incidence of CE formation in cultures treated with optimal NaB concentrations, further implicating endogenous TGF-beta activity in the NaB-initiated NHEK differentiation model. | nab | transforming growth factor beta 1 | Homo sapiens |
| 7 | Neutralizing antibodies to TGF-beta, moreover, effectively reduced the incidence of CE formation in cultures treated with optimal NaB concentrations, further implicating endogenous TGF-beta activity in the NaB-initiated NHEK differentiation model. | nab | transforming growth factor beta 1 | Homo sapiens |
| 8 | Neutralizing antibodies to TGF-beta, moreover, effectively reduced the incidence of CE formation in cultures treated with optimal NaB concentrations, further implicating endogenous TGF-beta activity in the NaB-initiated NHEK differentiation model. | nab | transforming growth factor beta 1 | Homo sapiens |
| 9 | It is suggested, therefore, that within the NaB-induced pathway of NHEK differentiation, TGF-beta can positively modulate expression of the differentiated phenotype but alone is insufficient for generation of mature CEs. | nab | transforming growth factor beta 1 | Homo sapiens |