Title : Capillary electrophoresis assay for G protein-coupled receptor-mediated GTPase activity.

Pub. Date : 2007 Feb 1

PMID : 17263349






1 Functional Relationships(s)
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1 Using the assay, the alpha2a adrenoceptor agonist UK14,304 was shown to simulate specific production of *GDP in membranes from HEK293T cells expressing receptor-G protein fusion to 525% of basal levels with an EC50 of 0.48 +/- 0.20 microM. Guanosine Diphosphate adrenoceptor alpha 2A Homo sapiens