Title : A dominant-negative form of the major human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents.

Pub. Date : 2007 Jan

PMID : 17259346






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This mutant form of APE1, termed ED, possesses two amino acid substitutions at active site residues Glu(96) (changed to Gln) and Asp(210) (changed to Asn). Aspartic Acid apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens