Title : Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate.

Pub. Date : 2007 Mar 22

PMID : 17258194






1 Functional Relationships(s)
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1 The evaluation of nuclear factor-kappaB (NF-kappaB) pathway revealed that topical treatment with alpha-amyrin is able to prevent IkappaB alpha degradation, p65/RelA phosphorylation and NF-kappaB activation. beta-amyrin nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus