Title : Synthesis and cell-based activity of a potent and selective protein tyrosine phosphatase 1B inhibitor prodrug.

Pub. Date : 2007 Feb 22

PMID : 17249650






1 Functional Relationships(s)
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1 The prodrug exhibits nanomolar PTP1B inhibitory activity in this assay, confirming the efficacy of intracellular phosphonate delivery using this prodrug approach. Organophosphonates protein tyrosine phosphatase non-receptor type 1 Homo sapiens