Title : Interaction of NPY compounds with the rat glucocorticoid-induced receptor (GIR) reveals similarity to the NPY-Y2 receptor.

Pub. Date : 2007 Feb

PMID : 17240481






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BIIE0246, a specific Y(2) antagonist, displaced (125)I-PYY(3-36) binding to rGIR with high affinity (95nM). BIIE 0246 G protein-coupled receptor 83 Rattus norvegicus
2 Activation of (35)S-GTPgammaS binding by Y(2)-selective agonist in rGIR transfected cells was also completely abolished by BIIE0246. BIIE 0246 G protein-coupled receptor 83 Rattus norvegicus