Pub. Date : 2007 Feb
PMID : 17237315
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We conducted a randomized, placebo-controlled, double-blind crossover study to investigate the effect of an 8-wk isolated isoflavone supplementation (84 mg/d) on serum concentrations of total IGF-I, free IGF-I, total IGF-II, IGF binding protein (BP)-1, IGFBP-2, and IGFBP-3. | Isoflavones | insulin like growth factor 1 | Homo sapiens |
2 | Interestingly, the change in serum IGF-I concentrations after isoflavone supplementation was negatively associated with serum equol concentrations (r=-0.49, P=0.002). | Isoflavones | insulin like growth factor 1 | Homo sapiens |
3 | However, to our knowledge, this is the first study that suggests isoflavones might have an IGF-I lowering effect in equol producers only. | Isoflavones | insulin like growth factor 1 | Homo sapiens |