Title : Anti-fibrotic effects of tetrandrine on bile-duct ligated rats.

Pub. Date : 2006 Oct

PMID : 17218962






2 Functional Relationships(s)
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1 Both Tet and silymarin treatments decreased the number of alpha-SMA- and NFkappaB-positive cells in fibrotic livers. Silymarin actin gamma 2, smooth muscle Rattus norvegicus
2 Moreover, Tet and silymarin treatments attenuated the mRNA expression levels of TGF-beta1,alpha-SMA, collagen 1alpha2, iNOS, ICAM-1, VEGF, and VEGFR2 genes, and induced the mRNA expression of the metallothionein gene. Silymarin actin gamma 2, smooth muscle Rattus norvegicus