Title : Redox sensitivity of the ryanodine receptor interaction with FK506-binding protein.

Pub. Date : 2007 Mar 9

PMID : 17200109






2 Functional Relationships(s)
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1 Using co-immunoprecipitation assays of solubilized native RyR2 from cardiac muscle sarcoplasmic reticulum (SR) with recombinant [(35)S]FKBP12.6, we found that the sulfydryl-oxidizing agents, H(2)O(2) and diamide, result in diminished RyR2-FKBP12.6 binding. sulfydryl ryanodine receptor 2 Homo sapiens
2 Using co-immunoprecipitation assays of solubilized native RyR2 from cardiac muscle sarcoplasmic reticulum (SR) with recombinant [(35)S]FKBP12.6, we found that the sulfydryl-oxidizing agents, H(2)O(2) and diamide, result in diminished RyR2-FKBP12.6 binding. sulfydryl ryanodine receptor 2 Homo sapiens