Title : ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives.

Pub. Date : 2007 Feb 15

PMID : 17188490






1 Functional Relationships(s)
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1 An X-ray co-crystal of structure 11 revealed that the oxime moiety was mimicking the C-ring of genistein, as previously predicted by SAR and docking studies. Oximes sarcosine dehydrogenase Homo sapiens