Title : Baicalin attenuates oxygen-glucose deprivation-induced injury via inhibiting NMDA receptor-mediated 5-lipoxygenase activation in rat cortical neurons.

Pub. Date : 2007 Feb

PMID : 17187986






1 Functional Relationships(s)
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1 During 0.5- to 2-h recovery after 1.5-h OGD, the production of 5-LOX metabolites, cysteinyl leukotrienes, was increased; this increased production was inhibited by baicalin and MK-801, while both the increased and baseline production were inhibited by caffeic acid. cysteinyl-leukotriene arachidonate 5-lipoxygenase Rattus norvegicus