Title : Characterization of Treponema denticola pyrF encoding orotidine-5'-monophosphate decarboxylase.

Pub. Date : 2007 Mar

PMID : 17187656






4 Functional Relationships(s)
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1 In complex medium, growth of the pyrF mutant was independent of added uracil, indicating activity of a uracil uptake/salvage pathway. Uracil orotidine-5'-phosphate decarboxylase Treponema denticola ATCC 35405
2 Transcription of pyrF was greatly reduced in T. denticola grown in excess uracil, demonstrating that de novo pyrimidine synthesis is regulated and suggesting a feedback mechanism. Uracil orotidine-5'-phosphate decarboxylase Treponema denticola ATCC 35405
3 Treponema denticola PyrF complemented uracil auxotrophy in an Escherichia coli pyrF mutant. Uracil orotidine-5'-phosphate decarboxylase Treponema denticola ATCC 35405
4 Treponema denticola PyrF complemented uracil auxotrophy in an Escherichia coli pyrF mutant. Uracil orotidine-5'-phosphate decarboxylase Treponema denticola ATCC 35405