Title : Microsomal prostaglandin E synthase-1 deficiency is associated with elevated peroxisome proliferator-activated receptor gamma: regulation by prostaglandin E2 via the phosphatidylinositol 3-kinase and Akt pathway.

Pub. Date : 2007 Feb 23

PMID : 17186945






1 Functional Relationships(s)
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1 We further show that basal mPGES-1-derived PGE(2) suppresses the expression of PPARgamma through a cAMP-independent pathway involving phosphatidylinositol 3-kinase and Akt signaling. Cyclic AMP prostaglandin E synthase Mus musculus