Title : Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain.

Pub. Date : 2007 Feb

PMID : 17182843






1 Functional Relationships(s)
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1 Notably, the binding activity to phosphatidylserine is inhibited by a physiological range of the Ca(2+) concentration attained after secretagogue stimulation, which presents a striking contrast to the Ca(2+)-stimulatory activity of the C2A domain of synaptotagmin I. Phosphatidylserines synaptotagmin 1 Homo sapiens