Title : The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae.

Pub. Date : 2007 Mar

PMID : 17179087






1 Functional Relationships(s)
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Protein Name
Organism
1 Although dipeptides and tripeptides with a normal peptide bond such as cys-gly or glu-cys-gly required the presence of only a functional DUG1 gene that encoded a protein belonging to the M20A metallohydrolase family, the presence of an unusual peptide bond such as in the dipeptide, gamma-glu-cys, or in GSH, required the participation of the DUG2 and DUG3 gene products as well. Glu-Cys-Gly metallodipeptidase Saccharomyces cerevisiae S288C