Title : Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation.

Pub. Date : 2006 Dec 15

PMID : 17178895






1 Functional Relationships(s)
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1 Furthermore, we show that Ron overexpression leads to receptor phosphorylation and is associated with elevated levels of tyrosine phosphorylated beta-catenin and the up-regulation of genes, including cyclin D1 and c-myc, which are associated with poor prognosis in patients with human breast cancers. Tyrosine macrophage stimulating 1 receptor Homo sapiens