Title : Asbestos redirects nitric oxide signaling through rapid catalytic conversion to nitrite.

Pub. Date : 2006 Dec 15

PMID : 17178853






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We report here that exposure of human mesothelioma or lung carcinoma cells to nitric oxide (NO) in the presence of crocidolite asbestos resulted in a marked decrease in intracellular nitrosation and diminished NO-induced posttranslational modifications of tumor-associated proteins (hypoxia-inducible factor-1alpha and p53). Nitric Oxide tumor protein p53 Homo sapiens