Title : Phytoestrogens: new ligands for rat and human alpha-fetoprotein.

Pub. Date : 1991 Sep 24

PMID : 1716990






2 Functional Relationships(s)
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1 The binding of the lignans, enterolactone, enterodiol, nordihydroguaiaretic acid (NDGA), and the isoflavonic phytoestrogen equol, to human and rat alpha-fetoprotein (AFP) was studied. 2,3-bis(3'-hydroxybenzyl)butyrolactone alpha-fetoprotein Rattus norvegicus
2 They had differential inhibitory effects (NDGA greater than equol greater than enterolactone greater than enterodiol) on the binding of estrone and estradiol to rat AFP and the binding of unsaturated fatty acid to both rat and human AFP. 2,3-bis(3'-hydroxybenzyl)butyrolactone alpha-fetoprotein Rattus norvegicus