Title : Arsenic trioxide in hematological malignancies: the new discovery of an ancient drug.

Pub. Date : 2006 Dec

PMID : 17168655






1 Functional Relationships(s)
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1 Our pre-clinical studies showed that ATO is capable to induce cell death in acute leukemia cells but the apoptotic function is limited since it can induce also a mechanism of cell defense by activating pro-survival molecules such as MEK-ERK, Bcl-xL, Bcl-2. Arsenic Trioxide BCL2 like 1 Homo sapiens