Title : [Effects of vitamin C on apoptosis and proliferation inhibition of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro].

Pub. Date : 2006 Sep

PMID : 17166419






2 Functional Relationships(s)
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1 Western blotting analysis showed that the expression of Bax and Caspase-3 up-regulated by DON was markedly decreased, while the expression of Bcl-2 down-regulated by DON was increased by 25 micromol/L Vit C pretreatment (P < 0.05). deoxynivalenol BCL2 associated X, apoptosis regulator Homo sapiens
2 100 micromol/L Vit C pretreatment could further increase the expression of Bax and Caspase-3 of HPBMCs induced by DON, while no significant effects on the Bcl-2 expression induced by DON were seen. deoxynivalenol BCL2 associated X, apoptosis regulator Homo sapiens