Title : Phytic acid modulates in vitro IL-8 and IL-6 release from colonic epithelial cells stimulated with LPS and IL-1beta.

Pub. Date : 2007 Jan

PMID : 17160716






4 Functional Relationships(s)
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1 Phytic acid modulates in vitro IL-8 and IL-6 release from colonic epithelial cells stimulated with LPS and IL-1beta. Phytic Acid interleukin 1 beta Homo sapiens
2 The aim of this study was to examine the role of PA in immunologic function of intestinal epithelial cells by analyzing its effect on interleukin (IL)-8 and IL-6 secretion by colonocytes and its role in the response of these cells to bacterial lipopolysaccharides (LPS) and IL-1beta. Phytic Acid interleukin 1 beta Homo sapiens
3 PA had a suppressive effect on IL-8 basal release and it dose dependently reduced IL-8 secretion by colonocytes stimulated with LPS and IL-1beta. Phytic Acid interleukin 1 beta Homo sapiens
4 PA was also an efficient down-regulator of IL-6 secretion stimulated by binary actions of LPS and IL-1beta. Phytic Acid interleukin 1 beta Homo sapiens