Title : Hydroxyl groups in the betabeta sandwich of metallo-beta-lactamases favor enzyme activity: Tyr218 and Ser262 pull down the lid.

Pub. Date : 2007 Feb 9

PMID : 17157873






1 Functional Relationships(s)
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1 In an effort to elucidate the molecular mechanisms involved in enhanced activity, we carried out molecular dynamics simulations of ten MBL variants in complex with a cefotaxime intermediate. Cefotaxime mannose-binding lectin family member 3, pseudogene Homo sapiens