Title : UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics.

Pub. Date : 2007 Mar

PMID : 17151191






1 Functional Relationships(s)
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1 Although UGT1A8 and 1A3 also catalyzed the glucuronidation of etoposide, their activities were approximately 10 and 1% of UGT1A1. Etoposide UDP glucuronosyltransferase family 1 member A8 Homo sapiens