Title : The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity.

Pub. Date : 2007 Feb 16

PMID : 17150966






3 Functional Relationships(s)
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Protein Name
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1 The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity. Lysine ribonuclease A family member 7 Homo sapiens
2 NMR studies showed that the 22 positively charged residues (Lys(18) and Arg(4)) are distributed into three clusters on the surface of hRNase7. Lysine ribonuclease A family member 7 Homo sapiens
3 We suggest that the hRNase7 binds to bacterial membrane and renders the membrane permeable through the flexible and clustered Lys residues K(1),K(3),K(111),K(112). Lysine ribonuclease A family member 7 Homo sapiens