Title : Toxin-dependent utilization of engineered ribosomal protein L3 limits trichothecene resistance in transgenic plants.

Pub. Date : 2004 Jul

PMID : 17134394






4 Functional Relationships(s)
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1 Toxin-dependent utilization of engineered ribosomal protein L3 limits trichothecene resistance in transgenic plants. Trichothecenes ribosomal 60S subunit protein L3 Saccharomyces cerevisiae S288C
2 Using yeast as a model system, we have identified several mutations in the gene encoding ribosomal protein L3 (Rpl3), which confer semi-dominant resistance to trichothecenes. Trichothecenes ribosomal 60S subunit protein L3 Saccharomyces cerevisiae S288C
3 Using yeast as a model system, we have identified several mutations in the gene encoding ribosomal protein L3 (Rpl3), which confer semi-dominant resistance to trichothecenes. Trichothecenes ribosomal 60S subunit protein L3 Saccharomyces cerevisiae S288C
4 This toxin-dependent utilization of the resistance-conferring Rpl3 protein could seriously limit efforts to utilize the identified target alterations in transgenic crops to increase trichothecene tolerance and Fusarium resistance. Trichothecenes ribosomal 60S subunit protein L3 Saccharomyces cerevisiae S288C