Title : HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.

Pub. Date : 2006 Nov

PMID : 17132220






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Downregulation of P-Akt decreased VEGF secretion in a manner similar to that of nelfinavir, but the combination of the two had no greater effect, consistent with the idea that nelfinavir decreases VEGF through the PI3K/Akt pathway. Nelfinavir AKT serine/threonine kinase 1 Homo sapiens