Title : Synergistic effect of cytochrome P450 epoxygenase CYP2J2*7 polymorphism with smoking on the onset of premature myocardial infarction.

Pub. Date : 2007 Nov

PMID : 17126841






1 Functional Relationships(s)
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1 OBJECTIVES: Cytochrome P450 (CYP) 2J2 is expressed in vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which are potent endogenous vasodilators and inhibitors of vascular inflammation. eets cytochrome P450 family 2 subfamily J member 2 Homo sapiens