Title : Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

Pub. Date : 2006 Dec 14

PMID : 17122773






1 Functional Relationships(s)
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1 Here we show that treatment with the cyclin-dependent kinase (CDK) inhibitor (R)-roscovitine does indeed yield effective arrest of cystic disease in jck and cpk mouse models of PKD. Roscovitine cystin 1 Mus musculus