Title : Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak.

Pub. Date : 2006 Nov

PMID : 17121941






1 Functional Relationships(s)
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1 The BITC-induced apoptosis correlated with induction of proapoptotic proteins Bax (MCF-7) and Bak (MDA-MB-231 and MCF-7) and down-regulation of antiapoptotic proteins Bcl-2 and Bcl-xL (MDA-MB-231). benzyl isothiocyanate BCL2 like 1 Homo sapiens