Title : Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells.

Pub. Date : 2006 Dec

PMID : 17119452






1 Functional Relationships(s)
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1 Induction of apoptosis involved an increase in the levels of p53, p21 and cellular Ca, and a decrease in mitochondrial membrane potential and activation of caspase 3 before culminating in apoptosis in sodium ascorbate-treated A375.S2 cells. Ascorbic Acid caspase 3 Homo sapiens