Title : The role of reactive oxygen species in the antitumor activity of bleomycin.

Pub. Date : 1990

PMID : 1710590






1 Functional Relationships(s)
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1 These results indicate that NADH-cytochrome b5 reductase catalyzes redox cycling of the bleomycin-Fe-complex which results in the formation of reactive oxygen species which oxidize deoxyribose as well as bases of DNA. Deoxyribose cytochrome b5 type A Rattus norvegicus