Title : [Effect of nociceptin on histamine and serotonin release in the central nervous system].

Pub. Date : 2006

PMID : 17094659






5 Functional Relationships(s)
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1 [Effect of nociceptin on histamine and serotonin release in the central nervous system]. Histamine prepronociceptin Rattus norvegicus
2 Role in pain sensation of both nociceptin (NC), the bioactive heptadecapeptide sequence of preproorphaninFQ and of histamine has been widely evidenced in the central nervous system (CNS). Histamine prepronociceptin Rattus norvegicus
3 Role in pain sensation of both nociceptin (NC), the bioactive heptadecapeptide sequence of preproorphaninFQ and of histamine has been widely evidenced in the central nervous system (CNS). Histamine prepronociceptin Rattus norvegicus
4 administered NC (5.5 nmol/rat) on histamine and serotonin levels in blood plasma, CSF and brain areas (hypothalamus and hippocampus) was studies and compared to the effect of the mast cell degranulator Compound 48/80(100microg/kg, i.c.v.) Histamine prepronociceptin Rattus norvegicus
5 NC could release histamine from both the mast cells and the neurons and it decreased CNS serotonin levels. Histamine prepronociceptin Rattus norvegicus