Pub. Date : 2006 Aug
PMID : 17081403
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: CaSR protein was detected in rat cardiac tissue and CaSR activator gadolinium (GdCl3) induced cardiomyocyte apoptosis and increased ERK1/2 phosphorylation and expression of BCl2 and activated Caspase3. | Gadolinium | calcium-sensing receptor | Rattus norvegicus |
| 2 | RESULTS: CaSR protein was detected in rat cardiac tissue and CaSR activator gadolinium (GdCl3) induced cardiomyocyte apoptosis and increased ERK1/2 phosphorylation and expression of BCl2 and activated Caspase3. | Gadolinium | calcium-sensing receptor | Rattus norvegicus |
| 3 | CONCLUSION: Our results demonstrate the CaSR existence in cardiomyocytes and CaSR activation by gadolinium can induce myocyte apoptosis by activating Caspase3 and tyrosine protein kinase pathway. | Gadolinium | calcium-sensing receptor | Rattus norvegicus |
| 4 | CONCLUSION: Our results demonstrate the CaSR existence in cardiomyocytes and CaSR activation by gadolinium can induce myocyte apoptosis by activating Caspase3 and tyrosine protein kinase pathway. | Gadolinium | calcium-sensing receptor | Rattus norvegicus |