Title : Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck.

Pub. Date : 2007 Mar 1

PMID : 17078813






1 Functional Relationships(s)
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Protein Name
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1 Inhibition with siRNA (small interfering RNA) targeting the SFK Lck, but not dominant-negative JAK (Janus kinase), prevented Cr(VI)-stimulated phosphorylation of both STAT3 isoforms and induction of IL-6. chromium hexavalent ion signal transducer and activator of transcription 3 Homo sapiens