Title : Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice.

Pub. Date : 2007 Feb 12

PMID : 17077276






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Urinary loss of cys-gly together with lower concentrations of cysteine, glycine, and oxoproline in kidney tissue and altered expression of mRNA and proteins involved in glutathione (GSH) metabolism suggests that PEPT2 is predominantly a system for reabsorption of cys-gly originating from GSH break-down, thus contributing to resynthesis of GSH. cysteinylglycine solute carrier family 15 (H+/peptide transporter), member 2 Mus musculus
2 Urinary loss of cys-gly together with lower concentrations of cysteine, glycine, and oxoproline in kidney tissue and altered expression of mRNA and proteins involved in glutathione (GSH) metabolism suggests that PEPT2 is predominantly a system for reabsorption of cys-gly originating from GSH break-down, thus contributing to resynthesis of GSH. cysteinylglycine solute carrier family 15 (H+/peptide transporter), member 2 Mus musculus