Title : The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer.

Pub. Date : 1991 Jan 11

PMID : 1707162






1 Functional Relationships(s)
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Protein Name
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1 Like Cyclosporin A (CsA), the macrolide FK 506 is a potent immunosuppressive that inhibits early steps of T cell activation, including the synthesis of Interleukin 2 (II-2) and numerous other lymphokines. Tacrolimus ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens