Title : The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.

Pub. Date : 2007 Jan

PMID : 17060455

1 Functional Relationships(s)
Compound Name
Protein Name
1 This provides new molecular insights into regulation of the neutrophil NADPH oxidase, suggesting that chemoattractant-stimulated superoxide production can be amplified by a positive feedback loop in which p67(phox) targets Vav1-mediated Rac activation. Superoxides CD33 molecule Homo sapiens