Title : The receptor-bound "empty pocket" state of the heterotrimeric G-protein alpha-subunit is conformationally dynamic.

Pub. Date : 2006 Oct 31

PMID : 17059215






1 Functional Relationships(s)
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1 Here, it is shown that both light-activated rhodopsin and the soluble mimic of R form trapped intermediate complexes with a GDP-released "empty pocket" state of the heterotrimer in the absence of GTP (or GTPgammaS). Guanosine Diphosphate rhodopsin Homo sapiens