Title : Vav proteins in neutrophils are required for FcgammaR-mediated signaling to Rac GTPases and nicotinamide adenine dinucleotide phosphate oxidase component p40(phox).

Pub. Date : 2006 Nov 1

PMID : 17056570






1 Functional Relationships(s)
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1 Clustering of FcgammaRs results in the activation of Vav proteins, Rho/Rac guanine nucleotide exchange factors, and results in robust superoxide generation through the NADPH oxidase. Superoxides vav 1 oncogene Mus musculus