Title : Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.

Pub. Date : 2006 Dec 5

PMID : 17052670






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PD98059 (an inhibitor of ERK) or LY294002 (an inhibitor of Akt), but not an inhibitor of p38 MAPK and JNK, significantly decreased cell viability and increased lactate dehydrogenase (LDH) release. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one AKT serine/threonine kinase 1 Homo sapiens