Title : Diesel exhaust particulate-induced activation of Stat3 requires activities of EGFR and Src in airway epithelial cells.

Pub. Date : 2007 Feb

PMID : 17028263






2 Functional Relationships(s)
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1 Inhibition of epidermal growth factor receptor (EGFR) and Src activities by the inhibitors PD-153035 and PP2, respectively, abolished the activation of Stat3 by DEP, suggesting that Stat3 activation by DEP requires EGFR and Src kinase activation. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline signal transducer and activator of transcription 3 Homo sapiens
2 Inhibition of epidermal growth factor receptor (EGFR) and Src activities by the inhibitors PD-153035 and PP2, respectively, abolished the activation of Stat3 by DEP, suggesting that Stat3 activation by DEP requires EGFR and Src kinase activation. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline signal transducer and activator of transcription 3 Homo sapiens