Title : Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.

Pub. Date : 2006 Oct 1

PMID : 17018621






1 Functional Relationships(s)
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1 Some therapeutic agents, such as bortezomib, not only induce proapoptotic Bcl-2 family members and active conformational changes in Bak and Bax but also are associated with undesirable effects, including accumulation of antiapoptotic proteins, such as Mcl-1. Bortezomib BCL2 associated X, apoptosis regulator Homo sapiens