Pub. Date : 2006
PMID : 17017928
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IgE-mediated hypersensitivity to cephalosporins. | Cephalosporins | immunoglobulin heavy constant epsilon | Homo sapiens |
| 2 | Like penicillins, cephalosporins may cause IgE-mediated reactions such as urticaria, angioedema, and anaphylactic shock, which occur because of sensitization to determinants shared with penicillins or to unique cephalosporin haptens. | Cephalosporins | immunoglobulin heavy constant epsilon | Homo sapiens |
| 3 | Like penicillins, cephalosporins may cause IgE-mediated reactions such as urticaria, angioedema, and anaphylactic shock, which occur because of sensitization to determinants shared with penicillins or to unique cephalosporin haptens. | Cephalosporins | immunoglobulin heavy constant epsilon | Homo sapiens |
| 4 | As far as in vitro tests are concerned, IgE assays for cephalosporins, specifically sepharose-radioimmunoassays, are a potentially useful tool in evaluating immediate reactions and could be used as complementary tests. | Cephalosporins | immunoglobulin heavy constant epsilon | Homo sapiens |
| 5 | In selected cases displaying negative results in both skin tests and IgE assays, a graded challenge with the implicated cephalosporin can be performed. | Cephalosporins | immunoglobulin heavy constant epsilon | Homo sapiens |
| 6 | Cephalosporin IgE-mediated hypersensitivity may be a transient condition; therefore, allergologic exams should be repeated in patients with negative initial allergologic work-ups, including challenges. | Cephalosporins | immunoglobulin heavy constant epsilon | Homo sapiens |