Pub. Date : 2006 Nov
PMID : 17016579
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We present a colon cancer patient with the UGT1A1 polymorphism (UGT1A1 *28) as a known high risk for irinotecan, who was treated with a combination of doxifluridine and irinotecan for peritoneal dissemination resulting in stable disease for 2 years without adverse reactions, although the patient initially developed severe adverse effects to the combination of the protracted venous infusion of 5-FU and irinotecan. | Fluorouracil | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
2 | We present a colon cancer patient with the UGT1A1 polymorphism (UGT1A1 *28) as a known high risk for irinotecan, who was treated with a combination of doxifluridine and irinotecan for peritoneal dissemination resulting in stable disease for 2 years without adverse reactions, although the patient initially developed severe adverse effects to the combination of the protracted venous infusion of 5-FU and irinotecan. | Fluorouracil | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |