Title : ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib.

Pub. Date : 2006 Dec

PMID : 16995874






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ZD6474 induced growth arrest and apoptosis of GIST-T1 cells in association with blockade of c-Kit and its downstream effectors, including Akt and extracellular signal-regulated kinase (ERK). vandetanib KIT proto-oncogene, receptor tyrosine kinase Homo sapiens