Title : Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.

Pub. Date : 2006 Dec 1

PMID : 16987662






1 Functional Relationships(s)
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1 This Letter describes the synthesis and SAR, developed through an iterative analog library approach, of potent and selective non-sarcosine-derived GlyT1 inhibitors. Sarcosine sarcosine dehydrogenase Homo sapiens