Title : Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo.

Pub. Date : 2006 Sep 15

PMID : 16982764






1 Functional Relationships(s)
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1 Inoculation of PC-3 cells pretreated with SAM and MBD2-AS into the flank of male BALB/c nu/nu mice resulted in the development of tumors of significantly smaller volume compared with animals inoculated with PC-3 cells treated with vehicle alone or MBD2 scrambled oligonucleotide. Oligonucleotides methyl-CpG binding domain protein 2 Mus musculus