Pub. Date : 2006 Nov-Dec
PMID : 16955376
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 99mTc-Sestamibi, a sensitive probe for in vivo imaging of P-glycoprotein inhibition by modulators and mdr1 antisense oligodeoxynucleotides. | Technetium Tc 99m Sestamibi | phosphoglycolate phosphatase | Mus musculus |
| 2 | PURPOSE: We tested the suitability of (99m)Tc-sestamibi to image the inhibition of P-glycoprotein (Pgp)-mediated multidrug resistance in tumor cells and xenografts after antisense treatment and/or inhibition with a novel Pgp modulator WK-X-34. | Technetium Tc 99m Sestamibi | phosphoglycolate phosphatase | Mus musculus |
| 3 | PURPOSE: We tested the suitability of (99m)Tc-sestamibi to image the inhibition of P-glycoprotein (Pgp)-mediated multidrug resistance in tumor cells and xenografts after antisense treatment and/or inhibition with a novel Pgp modulator WK-X-34. | Technetium Tc 99m Sestamibi | phosphoglycolate phosphatase | Mus musculus |
| 4 | CONCLUSIONS: (99m)Tc-sestamibi is a sensitive probe to monitor Pgp inhibition by different mechanisms in vivo in tumor xenografts. | Technetium Tc 99m Sestamibi | phosphoglycolate phosphatase | Mus musculus |